4WFR

Catalytic domain of mouse 2',3'-cyclic nucleotide 3'- phosphodiesterase, with mutation T232A, complexed with 2'-AMP

Summary for 4WFR

Descriptor2',3'-cyclic-nucleotide 3'-phosphodiesterase, ADENOSINE-2'-MONOPHOSPHATE (3 entities in total)
Functional Keywordshydrolase, myelin, nervous system
Biological sourceMus musculus (Mouse)
Cellular locationMembrane ; Lipid-anchor  P16330
Total number of polymer chains1
Total molecular weight24611.12
Authors
Myllykoski, M.,Raasakka, A.,Kursula, P. (deposition date: 2014-09-17, release date: 2015-09-30, Last modification date: 2018-01-17)
Primary citation
Raasakka, A.,Myllykoski, M.,Laulumaa, S.,Lehtimaki, M.,Hartlein, M.,Moulin, M.,Kursula, I.,Kursula, P.
Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase.
Sci Rep, 5:16520-16520, 2015
PubMed: 26563764 (PDB entries with the same primary citation)
DOI: 10.1038/srep16520
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.27010 3.0% 2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25