4WF8
Crystal structure of NS3/4A protease in complex with Asunaprevir
Summary for 4WF8
Entry DOI | 10.2210/pdb4wf8/pdb |
Descriptor | NS3 protein, ZINC ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | hcv protease inhibitor complex, resistance, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Hepatitis C virus |
Total number of polymer chains | 1 |
Total formula weight | 21105.05 |
Authors | Schiffer, C.A.,Soumana, D.I.,Ali, A. (deposition date: 2014-09-13, release date: 2014-10-08, Last modification date: 2023-12-27) |
Primary citation | Soumana, D.I.,Ali, A.,Schiffer, C.A. Structural Analysis of Asunaprevir Resistance in HCV NS3/4A Protease. Acs Chem.Biol., 9:2485-2490, 2014 Cited by PubMed: 25243902DOI: 10.1021/cb5006118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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