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4WF8

Crystal structure of NS3/4A protease in complex with Asunaprevir

Summary for 4WF8
Entry DOI10.2210/pdb4wf8/pdb
DescriptorNS3 protein, ZINC ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordshcv protease inhibitor complex, resistance, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHepatitis C virus
Total number of polymer chains1
Total formula weight21105.05
Authors
Schiffer, C.A.,Soumana, D.I.,Ali, A. (deposition date: 2014-09-13, release date: 2014-10-08, Last modification date: 2023-12-27)
Primary citationSoumana, D.I.,Ali, A.,Schiffer, C.A.
Structural Analysis of Asunaprevir Resistance in HCV NS3/4A Protease.
Acs Chem.Biol., 9:2485-2490, 2014
Cited by
PubMed: 25243902
DOI: 10.1021/cb5006118
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

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