4WF8

Crystal structure of NS3/4A protease in complex with Asunaprevir

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
A	0019087	biological_process	transformation of host cell by virus

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1201

Chain	Residue
A	CYS1097
A	CYS1099
A	CYS1145
A	HIS1149

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site_id	AC2
Number of Residues	5
Details	binding site for residue CL A 1202

Chain	Residue
A	ILE994
A	ARG1011
A	ASP1025
A	ASN1027
A	HOH1350

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site_id	AC3
Number of Residues	23
Details	binding site for residue 2R9 A 1203

Chain	Residue
A	ARG997
A	TYR1006
A	ALA1007
A	GLN1008
A	GLU1030
A	PHE1043
A	HIS1057
A	VAL1078
A	ASP1081
A	ARG1123
A	ILE1132
A	LEU1135
A	LYS1136
A	GLY1137
A	SER1139
A	PHE1154
A	ARG1155
A	ALA1156
A	ALA1157
A	ASP1168
A	HOH1363
A	HOH1385
A	HOH1394

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