4WEG
influenza virus neuraminidase N9 in complex 2,3-difluorosialic acid
Summary for 4WEG
Entry DOI | 10.2210/pdb4weg/pdb |
Related | 1NNC 4WEF |
Descriptor | Neuraminidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | influenza virus neuraminidase, n9, complex, 2, 3-difluorosialic acid, second binding site, hydrolase |
Biological source | Influenza A virus (A/tern/Australia/G70C/1975(H11N9)) |
Cellular location | Virion membrane : P03472 |
Total number of polymer chains | 1 |
Total formula weight | 46772.46 |
Authors | Streltsov, V.A.,Pilling, P.,Barrett, S.,McKimm-Breschkin, J. (deposition date: 2014-09-10, release date: 2015-09-16, Last modification date: 2020-07-29) |
Primary citation | Streltsov, V.A.,Pilling, P.,Barrett, S.,McKimm-Breschkin, J.L. Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN) Antiviral Res., 123:216-223, 2015 Cited by PubMed: 26364554DOI: 10.1016/j.antiviral.2015.08.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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