4WBO

Bovine G Protein Coupled Receptor Kinase 1 in Complex with Amlexanox

4WBO の概要

• エントリーDOI: 10.2210/pdb4wbo/pdb
• 関連するPDBエントリー: 4L9I
• 分子名称: Rhodopsin kinase, 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: g-protein-coupled receptor kinase 1, amlexanox, phosphorylation, protein conformation, protein kinase inhibitors, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Bos taurus (Bovine)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 246197.84

構造登録者

Homan, K.T.,Tesmer, J.J.G. (登録日: 2014-09-03, 公開日: 2014-11-05, 最終更新日: 2023-12-27)

• 主引用文献: Homan, K.T.,Wu, E.,Cannavo, A.,Koch, W.J.,Tesmer, J.J.; Identification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor.; Molecules, 19:16937-16949, 2014; PubMed: 25340299; DOI: 10.3390/molecules191016937

実験手法

X-RAY DIFFRACTION (2.81 Å)