4W4O

High-resolution crystal structure of Fc bound to its human receptor Fc-gamma-RI

4W4O の概要

• エントリーDOI: 10.2210/pdb4w4o/pdb
• 関連するPDBエントリー: 4W4N
• 分子名称: Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: immune complex igg1 protein-protein complex asymmetry, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 87850.19

構造登録者

Caaveiro, J.M.M.,Kiyoshi, M.,Tsumoto, K. (登録日: 2014-08-15, 公開日: 2015-04-29, 最終更新日: 2023-11-08)

• 主引用文献: Kiyoshi, M.,Caaveiro, J.M.M.,Kawai, T.,Tashiro, S.,Ide, T.,Asaoka, Y.,Hatayama, K.,Tsumoto, K.; Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI; Nat Commun, 6:6866-6866, 2015; PubMed: 25925696; DOI: 10.1038/ncomms7866

実験手法

X-RAY DIFFRACTION (1.8 Å)