4V9R
Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome
This is a non-PDB format compatible entry.
Summary for 4V9R
Entry DOI | 10.2210/pdb4v9r/pdb |
Related PRD ID | PRD_001218 |
Descriptor | 16S Ribosomal RNA, 30S Ribosomal Protein S10, 30S Ribosomal Protein S11, ... (61 entities in total) |
Functional Keywords | 70s, ribosome, dityromycin, ge82832, ribosomal protein s12, ef-g, translocation, dityromycin and ge82832 bind protein s12 and block ef-g catalyzed translocation, 30s subunit with bound mrna, p-site trna, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Thermus thermophilus More |
Total number of polymer chains | 110 |
Total formula weight | 4455124.47 |
Authors | Bulkley, D.P.,Brandi, L.,Polikanov, Y.S.,Fabbretti, A.,O'Connor, M.,Gualerzi, C.O.,Steitz, T.A. (deposition date: 2013-12-05, release date: 2014-07-09, Last modification date: 2014-12-10) |
Primary citation | Bulkley, D.,Brandi, L.,Polikanov, Y.S.,Fabbretti, A.,O'Connor, M.,Gualerzi, C.O.,Steitz, T.A. The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6:357-365, 2014 Cited by PubMed: 24412368DOI: 10.1016/j.celrep.2013.12.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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