Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution.

This is a large structure.

Summary for 4V4H

Related1VS6 1VS7 1VS8
Integrates1VS5 1VS6 1VS7 1VS8
Descriptor16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S3, 30S RIBOSOMAL PROTEIN S4, ... (55 entities in total)
Functional Keywordsribosome, kasugamycin
Biological sourceEscherichia coli
Total number of polymer chains104
Total molecular weight4301002.66
Schuwirth, B.S.,Vila-Sanjurjo, A.,Cate, J.H.D. (deposition date: 2006-08-04, release date: 2014-07-09, Last modification date: 2014-12-10)
Primary citation
Schuwirth, B.S.,Day, J.M.,Hau, C.W.,Janssen, G.R.,Dahlberg, A.E.,Cate, J.H.D.,Vila-Sanjurjo, A.
Structural analysis of kasugamycin inhibition of translation.
Nat.Struct.Mol.Biol., 13:879-886, 2006
PubMed: 16998486 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1150
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone4214.8%17.3%12.6%0.58MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload