4V2Z
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with Pomalidomide
Summary for 4V2Z
Entry DOI | 10.2210/pdb4v2z/pdb |
Related | 4V2Y 4V30 4V31 4V32 |
Descriptor | CEREBLON ISOFORM 4, ZINC ION, S-Pomalidomide, ... (4 entities in total) |
Functional Keywords | signaling protein, teratogenicity, aromatic cage, cc-4047, pomalyst |
Biological source | MAGNETOSPIRILLUM GRYPHISWALDENSE |
Total number of polymer chains | 3 |
Total formula weight | 42126.69 |
Authors | Hartmann, M.D.,Lupas, A.N.,Hernandez Alvarez, B. (deposition date: 2014-10-15, release date: 2014-12-17) |
Primary citation | Hartmann, M.D.,Boichenko, I.,Coles, M.,Zanini, F.,Lupas, A.N.,Hernandez Alvarez, B. Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon. J.Struct.Biol., 188:225-, 2014 Cited by PubMed: 25448889DOI: 10.1016/J.JSB.2014.10.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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