4V2V

JMJD2A COMPLEXED WITH NI(II), NOG AND HISTONE H3K27me3 PEPTIDE (25-29) ARK(me3)SA

Summary for 4V2V

• Entry DOI: 10.2210/pdb4v2v/pdb
• Related: 4V2W
• Descriptor: LYSINE-SPECIFIC DEMETHYLASE 4A, HISTONE H3.1T, N-OXALYLGLYCINE, ... (7 entities in total)
• Functional Keywords: oxidoreductase, non-heme, iron, 2-oxoglutarate, dioxygenase, oxygenase, double-stranded beta helix, dsbh, facial triad, jmjc domain, metal binding protein, epigenetic and transcription regulation, chromatin regulator, hydroxylation
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 90381.78

Authors

Chowdhury, R.,Madden, S.K.,Schofield, C.J. (deposition date: 2014-10-15, release date: 2014-11-05, Last modification date: 2024-01-10)

• Primary citation: Williams, S.T.,Walport, L.J.,Hopkinson, R.J.,Madden, S.K.,Chowdhury, R.,Schofield, C.J.,Kawamura, A.; Studies on the Catalytic Domains of Multiple Jmjc Oxygenases Using Peptide Substrates.; Epigenetics, 9:1596-, 2014; PubMed: 25625844; DOI: 10.4161/15592294.2014.983381

Experimental method

X-RAY DIFFRACTION (2 Å)