4UZK
STRUCTURE OF THE WNT DEACYLASE NOTUM FROM DROSOPHILA - CRYSTAL FORM II - 1.9A
Summary for 4UZK
Entry DOI | 10.2210/pdb4uzk/pdb |
Related | 4UYU 4UYW 4UYZ 4UZ1 4UZ5 4UZ6 4UZ7 4UZ9 4UZA 4UZJ 4UZL 4UZQ 4WBH |
Descriptor | NOTUM, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | hydrolase, esterase, extracellular, alpha/beta hydrolase |
Biological source | DROSOPHILA MELANOGASTER (FRUIT FLY) |
Total number of polymer chains | 2 |
Total formula weight | 85496.45 |
Authors | Zebisch, M.,Jones, E.Y. (deposition date: 2014-09-05, release date: 2015-02-25, Last modification date: 2020-07-29) |
Primary citation | Kakugawa, S.,Langton, P.F.,Zebisch, M.,Howell, S.A.,Chang, T.,Liu, Y.,Feizi, T.,Bineva, G.,O'Reilly, N.,Snijders, A.P.,Jones, E.Y.,Vincent, J. Notum Deacylates Wnt Proteins to Suppress Signalling Activity. Nature, 519:187-, 2015 Cited by PubMed: 25731175DOI: 10.1038/NATURE14259 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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