4UTN
Crystal structure of zebrafish Sirtuin 5 in complex with succinylated CPS1-peptide
Summary for 4UTN
Entry DOI | 10.2210/pdb4utn/pdb |
Related | 4UTR 4UTV 4UTX 4UTZ 4UU7 4UU8 4UUA 4UUB |
Descriptor | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL, SUCCINYL-CPS1-PEPTIDE, ZINC ION, ... (7 entities in total) |
Functional Keywords | hydrolase, regulatory enzyme, rossmann-fold, zinc-binding |
Biological source | DANIO RERIO (ZEBRAFISH) More |
Cellular location | Mitochondrion (By similarity): Q6DHI5 |
Total number of polymer chains | 3 |
Total formula weight | 62425.07 |
Authors | Pannek, M.,Gertz, M.,Steegborn, C. (deposition date: 2014-07-21, release date: 2014-08-20, Last modification date: 2024-01-10) |
Primary citation | Roessler, C.,Nowak, T.,Pannek, M.,Gertz, M.,Nguyen, G.T.,Scharfe, M.,Born, I.,Sippl, W.,Steegborn, C.,Schutkowski, M. Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors. Angew.Chem.Int.Ed.Engl., 53:10728-, 2014 Cited by PubMed: 25111069DOI: 10.1002/ANIE.201402679 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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