4UTN
Crystal structure of zebrafish Sirtuin 5 in complex with succinylated CPS1-peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL | polymer | 275 | 30423.8 | 2 | UniProt (Q6DHI5) Pfam (PF02146) | DANIO RERIO (ZEBRAFISH) | REGULATORY PROTEIN SIR2 HOMOLOG 5, SIRTUIN 5 |
| 2 | C (D) | SUCCINYL-CPS1-PEPTIDE | polymer | 9 | 1068.2 | 1 | HOMO SAPIENS | ||
| 3 | D, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 5 | G (B) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | H (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | I, J (A, B) | water | water | 18.0 | 17 | Chemie (HOH) |
Sequence modifications
A, B: 30 - 298 (UniProt: Q6DHI5)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Ile 25 | - | expression tag |
| Asp 26 | - | expression tag |
| Pro 27 | - | expression tag |
| Phe 28 | - | expression tag |
| Thr 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61915.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 509.3 | |
| All* | Total formula weight | 62425.1 |
