4UM3

Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920

4UM3 の概要

• エントリーDOI: 10.2210/pdb4um3/pdb
• 関連するPDBエントリー: 4UM1
• 分子名称: ACETYLCHOLINE BINDING PROTEIN, 1-(6-bromopyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: nicotinic acetylcholine receptor, ion channel, receptor stoichiometry, cys-loop receptor, signaling protein
• 由来する生物種: LYMNAEA STAGNALIS (GREAT POND SNAIL); 詳細
• 細胞内の位置: Secreted: P58154 P58154 P58154
• タンパク質・核酸の鎖数: 40
• 化学式量合計: 1053015.01

構造登録者

Shahsavar, A.,Kastrup, J.S.,Balle, T.,Gajhede, M. (登録日: 2014-05-14, 公開日: 2015-07-22, 最終更新日: 2024-01-10)

• 主引用文献: Shahsavar, A.,Ahring, P.K.,Olsen, J.A.,Krintel, C.,Kastrup, J.S.,Balle, T.,Gajhede, M.; Achbp Engineered to Mimic the Alpha4-Alpha4 Binding Pocket in Alpha4Beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity; Mol.Pharmacol., 88:697-, 2015; PubMed: 26180047; DOI: 10.1124/MOL.115.098061

実験手法