4UM3

Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0004888	molecular_function	transmembrane signaling receptor activity
a	0005216	molecular_function	monoatomic ion channel activity
a	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
a	0006811	biological_process	monoatomic ion transport
a	0016020	cellular_component	membrane
a	0034220	biological_process	monoatomic ion transmembrane transport
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
b	0004888	molecular_function	transmembrane signaling receptor activity
b	0005216	molecular_function	monoatomic ion channel activity
b	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
b	0006811	biological_process	monoatomic ion transport
b	0016020	cellular_component	membrane
b	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
c	0004888	molecular_function	transmembrane signaling receptor activity
c	0005216	molecular_function	monoatomic ion channel activity
c	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
c	0006811	biological_process	monoatomic ion transport
c	0016020	cellular_component	membrane
c	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
d	0004888	molecular_function	transmembrane signaling receptor activity
d	0005216	molecular_function	monoatomic ion channel activity
d	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
d	0006811	biological_process	monoatomic ion transport
d	0016020	cellular_component	membrane
d	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
e	0004888	molecular_function	transmembrane signaling receptor activity
e	0005216	molecular_function	monoatomic ion channel activity
e	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
e	0006811	biological_process	monoatomic ion transport
e	0016020	cellular_component	membrane
e	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport
f	0004888	molecular_function	transmembrane signaling receptor activity
f	0005216	molecular_function	monoatomic ion channel activity
f	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
f	0006811	biological_process	monoatomic ion transport
f	0016020	cellular_component	membrane
f	0034220	biological_process	monoatomic ion transmembrane transport
F	0004888	molecular_function	transmembrane signaling receptor activity
F	0005216	molecular_function	monoatomic ion channel activity
F	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
F	0006811	biological_process	monoatomic ion transport
F	0016020	cellular_component	membrane
F	0034220	biological_process	monoatomic ion transmembrane transport
g	0004888	molecular_function	transmembrane signaling receptor activity
g	0005216	molecular_function	monoatomic ion channel activity
g	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
g	0006811	biological_process	monoatomic ion transport
g	0016020	cellular_component	membrane
g	0034220	biological_process	monoatomic ion transmembrane transport
G	0004888	molecular_function	transmembrane signaling receptor activity
G	0005216	molecular_function	monoatomic ion channel activity
G	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
G	0006811	biological_process	monoatomic ion transport
G	0016020	cellular_component	membrane
G	0034220	biological_process	monoatomic ion transmembrane transport
h	0004888	molecular_function	transmembrane signaling receptor activity
h	0005216	molecular_function	monoatomic ion channel activity
h	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
h	0006811	biological_process	monoatomic ion transport
h	0016020	cellular_component	membrane
h	0034220	biological_process	monoatomic ion transmembrane transport
H	0004888	molecular_function	transmembrane signaling receptor activity
H	0005216	molecular_function	monoatomic ion channel activity
H	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
H	0006811	biological_process	monoatomic ion transport
H	0016020	cellular_component	membrane
H	0034220	biological_process	monoatomic ion transmembrane transport
i	0004888	molecular_function	transmembrane signaling receptor activity
i	0005216	molecular_function	monoatomic ion channel activity
i	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
i	0006811	biological_process	monoatomic ion transport
i	0016020	cellular_component	membrane
i	0034220	biological_process	monoatomic ion transmembrane transport
I	0004888	molecular_function	transmembrane signaling receptor activity
I	0005216	molecular_function	monoatomic ion channel activity
I	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
I	0006811	biological_process	monoatomic ion transport
I	0016020	cellular_component	membrane
I	0034220	biological_process	monoatomic ion transmembrane transport
j	0004888	molecular_function	transmembrane signaling receptor activity
j	0005216	molecular_function	monoatomic ion channel activity
j	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
j	0006811	biological_process	monoatomic ion transport
j	0016020	cellular_component	membrane
j	0034220	biological_process	monoatomic ion transmembrane transport
J	0004888	molecular_function	transmembrane signaling receptor activity
J	0005216	molecular_function	monoatomic ion channel activity
J	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
J	0006811	biological_process	monoatomic ion transport
J	0016020	cellular_component	membrane
J	0034220	biological_process	monoatomic ion transmembrane transport
k	0004888	molecular_function	transmembrane signaling receptor activity
k	0005216	molecular_function	monoatomic ion channel activity
k	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
k	0006811	biological_process	monoatomic ion transport
k	0016020	cellular_component	membrane
k	0034220	biological_process	monoatomic ion transmembrane transport
K	0004888	molecular_function	transmembrane signaling receptor activity
K	0005216	molecular_function	monoatomic ion channel activity
K	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
K	0006811	biological_process	monoatomic ion transport
K	0016020	cellular_component	membrane
K	0034220	biological_process	monoatomic ion transmembrane transport
l	0004888	molecular_function	transmembrane signaling receptor activity
l	0005216	molecular_function	monoatomic ion channel activity
l	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
l	0006811	biological_process	monoatomic ion transport
l	0016020	cellular_component	membrane
l	0034220	biological_process	monoatomic ion transmembrane transport
L	0004888	molecular_function	transmembrane signaling receptor activity
L	0005216	molecular_function	monoatomic ion channel activity
L	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
L	0006811	biological_process	monoatomic ion transport
L	0016020	cellular_component	membrane
L	0034220	biological_process	monoatomic ion transmembrane transport
m	0004888	molecular_function	transmembrane signaling receptor activity
m	0005216	molecular_function	monoatomic ion channel activity
m	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
m	0006811	biological_process	monoatomic ion transport
m	0016020	cellular_component	membrane
m	0034220	biological_process	monoatomic ion transmembrane transport
M	0004888	molecular_function	transmembrane signaling receptor activity
M	0005216	molecular_function	monoatomic ion channel activity
M	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
M	0006811	biological_process	monoatomic ion transport
M	0016020	cellular_component	membrane
M	0034220	biological_process	monoatomic ion transmembrane transport
n	0004888	molecular_function	transmembrane signaling receptor activity
n	0005216	molecular_function	monoatomic ion channel activity
n	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
n	0006811	biological_process	monoatomic ion transport
n	0016020	cellular_component	membrane
n	0034220	biological_process	monoatomic ion transmembrane transport
N	0004888	molecular_function	transmembrane signaling receptor activity
N	0005216	molecular_function	monoatomic ion channel activity
N	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
N	0006811	biological_process	monoatomic ion transport
N	0016020	cellular_component	membrane
N	0034220	biological_process	monoatomic ion transmembrane transport
O	0004888	molecular_function	transmembrane signaling receptor activity
O	0005216	molecular_function	monoatomic ion channel activity
O	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
O	0006811	biological_process	monoatomic ion transport
O	0016020	cellular_component	membrane
O	0034220	biological_process	monoatomic ion transmembrane transport
P	0004888	molecular_function	transmembrane signaling receptor activity
P	0005216	molecular_function	monoatomic ion channel activity
P	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
P	0006811	biological_process	monoatomic ion transport
P	0016020	cellular_component	membrane
P	0034220	biological_process	monoatomic ion transmembrane transport
Q	0004888	molecular_function	transmembrane signaling receptor activity
Q	0005216	molecular_function	monoatomic ion channel activity
Q	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Q	0006811	biological_process	monoatomic ion transport
Q	0016020	cellular_component	membrane
Q	0034220	biological_process	monoatomic ion transmembrane transport
R	0004888	molecular_function	transmembrane signaling receptor activity
R	0005216	molecular_function	monoatomic ion channel activity
R	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
R	0006811	biological_process	monoatomic ion transport
R	0016020	cellular_component	membrane
R	0034220	biological_process	monoatomic ion transmembrane transport
S	0004888	molecular_function	transmembrane signaling receptor activity
S	0005216	molecular_function	monoatomic ion channel activity
S	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
S	0006811	biological_process	monoatomic ion transport
S	0016020	cellular_component	membrane
S	0034220	biological_process	monoatomic ion transmembrane transport
T	0004888	molecular_function	transmembrane signaling receptor activity
T	0005216	molecular_function	monoatomic ion channel activity
T	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
T	0006811	biological_process	monoatomic ion transport
T	0016020	cellular_component	membrane
T	0034220	biological_process	monoatomic ion transmembrane transport
U	0004888	molecular_function	transmembrane signaling receptor activity
U	0005216	molecular_function	monoatomic ion channel activity
U	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
U	0006811	biological_process	monoatomic ion transport
U	0016020	cellular_component	membrane
U	0034220	biological_process	monoatomic ion transmembrane transport
V	0004888	molecular_function	transmembrane signaling receptor activity
V	0005216	molecular_function	monoatomic ion channel activity
V	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
V	0006811	biological_process	monoatomic ion transport
V	0016020	cellular_component	membrane
V	0034220	biological_process	monoatomic ion transmembrane transport
W	0004888	molecular_function	transmembrane signaling receptor activity
W	0005216	molecular_function	monoatomic ion channel activity
W	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
W	0006811	biological_process	monoatomic ion transport
W	0016020	cellular_component	membrane
W	0034220	biological_process	monoatomic ion transmembrane transport
X	0004888	molecular_function	transmembrane signaling receptor activity
X	0005216	molecular_function	monoatomic ion channel activity
X	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
X	0006811	biological_process	monoatomic ion transport
X	0016020	cellular_component	membrane
X	0034220	biological_process	monoatomic ion transmembrane transport
Y	0004888	molecular_function	transmembrane signaling receptor activity
Y	0005216	molecular_function	monoatomic ion channel activity
Y	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Y	0006811	biological_process	monoatomic ion transport
Y	0016020	cellular_component	membrane
Y	0034220	biological_process	monoatomic ion transmembrane transport
Z	0004888	molecular_function	transmembrane signaling receptor activity
Z	0005216	molecular_function	monoatomic ion channel activity
Z	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
Z	0006811	biological_process	monoatomic ion transport
Z	0016020	cellular_component	membrane
Z	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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