4UIS
The cryoEM structure of human gamma-Secretase complex
Summary for 4UIS
Entry DOI | 10.2210/pdb4uis/pdb |
EMDB information | 2974 |
Descriptor | GAMMA-SECRETASE, LYSOZYME, ... (5 entities in total) |
Functional Keywords | hydrolase, gamma-secretase |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Host cytoplasm : A0A097J809 |
Total number of polymer chains | 5 |
Total formula weight | 127307.88 |
Authors | |
Primary citation | Sun, L.,Zhao, L.,Yang, G.,Yan, C.,Zhou, R.,Zhou, X.,Xie, T.,Zhao, Y.,Wu, S.,Li, X.,Shi, Y. Structural Basis of Human Gamma-Secretase Assembly. Proc.Natl.Acad.Sci.USA, 112:6003-, 2015 Cited by PubMed: 25918421DOI: 10.1073/PNAS.1506242112 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.4 Å) |
Structure validation
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