4UFR

Structure of the ectodomain of LGR5 in complex with R-spondin-2 (Fu1Fu2)

Summary for 4UFR

• Entry DOI: 10.2210/pdb4ufr/pdb
• Related: 4UFS
• Descriptor: LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, R-SPONDIN-2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: signaling protein, wnt, lgr, rspo
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 4
• Total formula weight: 136653.57

Authors

Zebisch, M.,Jones, E.Y. (deposition date: 2015-03-18, release date: 2015-07-08, Last modification date: 2020-07-29)

• Primary citation: Zebisch, M.,Jones, E.Y.; Crystal Structure of R-Spondin 2 in Complex with the Ectodomains of its Receptors Lgr5 and Znrf3.; J.Struct.Biol., 191:149-, 2015; PubMed: 26123262; DOI: 10.1016/J.JSB.2015.05.008

Experimental method

X-RAY DIFFRACTION (2.2 Å)