4UDB

MR in complex with desisobutyrylciclesonide

Summary for 4UDB

• Entry DOI: 10.2210/pdb4udb/pdb
• Related: 4UDA 4UDC 4UDD
• Descriptor: MINERALOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 1, DIMETHYL SULFOXIDE, ... (7 entities in total)
• Functional Keywords: signaling protein, nuclear hormone receptor, ligand complex, peptide complex
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: P08235; Nucleus : Q15788
• Total number of polymer chains: 2
• Total formula weight: 34202.24

Authors

Edman, K.,Hogner, A.,Hussein, A.,Aagaard, A.,Backstrom, S.,Bodin, C.,Wissler, L.,JellesmarkJensen, T.,Cavallin, A.,Nilsson, E.,Lepisto, M.,Guallar, V. (deposition date: 2014-12-09, release date: 2015-11-25, Last modification date: 2023-12-20)

• Primary citation: Edman, K.,Hosseini, A.,Bjursell, M.K.,Aagaard, A.,Wissler, L.,Gunnarsson, A.,Kaminski, T.,Kohler, C.,Backstrom, S.,Jensen, T.J.,Cavallin, A.,Karlsson, U.,Nilsson, E.,Lecina, D.,Takahashi, R.,Grebner, C.,Geschwindner, S.,Lepisto, M.,Hogner, A.C.,Guallar, V.; Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints.; Structure, 23:2280-, 2015; PubMed: 26602186; DOI: 10.1016/J.STR.2015.09.012

Experimental method

X-RAY DIFFRACTION (2.36 Å)