4UDB
MR in complex with desisobutyrylciclesonide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 1984 |
| Chain | Residue |
| A | GLU867 |
| A | GLU868 |
| A | SER910 |
| A | ASN912 |
| A | ASN913 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1985 |
| Chain | Residue |
| A | HIS950 |
| A | GLU955 |
| A | PHE956 |
| A | GLN854 |
| A | GLN858 |
| A | ARG861 |
| A | SER949 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1986 |
| Chain | Residue |
| A | THR880 |
| A | HIS932 |
| A | VAL935 |
| A | SER936 |
| A | LEU939 |
| A | HOH2057 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CV7 A 1987 |
| Chain | Residue |
| A | LEU766 |
| A | LEU769 |
| A | ASN770 |
| A | ALA773 |
| A | GLN776 |
| A | LEU810 |
| A | ARG817 |
| A | PHE829 |
| A | MET845 |
| A | PHE941 |
| A | CYS942 |
| A | THR945 |
| A | VAL954 |
| A | PHE956 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for coactivator binding"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15908963","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YA3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15967794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AA5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AA6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 7"} |
| Chain | Residue | Details |
