4U7D
Structure of human RECQ-like helicase in complex with an oligonucleotide
Summary for 4U7D
Entry DOI | 10.2210/pdb4u7d/pdb |
Descriptor | ATP-dependent DNA helicase Q1, DNA oligonucleotide, ZINC ION (3 entities in total) |
Functional Keywords | hydrolase-dna complex, nuclear protein, hydrolase, dna strand annealing, dna binding protein, structural genomics, structural genomics consortium, sgc, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P46063 |
Total number of polymer chains | 8 |
Total formula weight | 294069.04 |
Authors | Pike, A.C.W.,Zhang, Y.,Schnecke, C.,Cooper, C.D.O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O.,Structural Genomics Consortium (SGC) (deposition date: 2014-07-30, release date: 2015-01-21, Last modification date: 2023-12-20) |
Primary citation | Pike, A.C.,Gomathinayagam, S.,Swuec, P.,Berti, M.,Zhang, Y.,Schnecke, C.,Marino, F.,von Delft, F.,Renault, L.,Costa, A.,Gileadi, O.,Vindigni, A. Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: Insights from DNA complex structures. Proc.Natl.Acad.Sci.USA, 112:4286-4291, 2015 Cited by PubMed: 25831490DOI: 10.1073/pnas.1417594112 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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