4U70
HsMetAP (F309M) in complex with (1-amino-2-cyclohexylethyl)phosphonic acid
Summary for 4U70
Entry DOI | 10.2210/pdb4u70/pdb |
Related | 4u1b 4u69 4u6c 4u6e 4u6j 4u6w 4u6z 4u71 4u73 4u75 4u76 |
Descriptor | Methionine aminopeptidase 1, COBALT (II) ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34802.40 |
Authors | Arya, T.,Addlagatta, A. (deposition date: 2014-07-30, release date: 2015-03-25, Last modification date: 2024-03-20) |
Primary citation | Arya, T.,Reddi, R.,Kishor, C.,Ganji, R.J.,Bhukya, S.,Gumpena, R.,McGowan, S.,Drag, M.,Addlagatta, A. Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58:2350-2357, 2015 Cited by PubMed: 25699713DOI: 10.1021/jm501790e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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