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4U70

HsMetAP (F309M) in complex with (1-amino-2-cyclohexylethyl)phosphonic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methionine aminopeptidase 1polymer30634438.21UniProt (P53582)
Pfam (PF00557)
Homo sapiens (Human)MetAP 1,Peptidase M 1
2B, C
(A)
COBALT (II) IONnon-polymer58.92Chemie (CO)
3D
(A)
POTASSIUM IONnon-polymer39.11Chemie (K)
4E
(A)
[(1R)-1-amino-2-cyclohexylethyl]phosphonic acidnon-polymer207.21Chemie (Q04)
5F
(A)
waterwater18.0398Chemie (HOH)
Sequence modifications
A: 90 - 395 (UniProt: P53582)
PDBExternal DatabaseDetails
Met 309Phe 300engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34438.2
Non-Polymers*Number of molecules4
Total formula weight364.2
All*Total formula weight34802.4
*Water molecules are not included.

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PDB entries from 2025-12-24

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