Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist FW and postitive modulator (R,R)-2b complex

Summary for 4U5C

DescriptorGlutamate receptor 2, Con-ikot-ikot, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
Functional Keywordsampa receptor, transport protein-toxin complex, transport protein/toxin
Biological sourceRattus norvegicus (Rat)
Cellular locationCell membrane; Multi-pass membrane protein P19491
Secreted  P0CB20
Total number of polymer chains6
Total molecular weight387762.41
Chen, L.,Gouaux, E. (deposition date: 2014-07-25, release date: 2014-08-13, Last modification date: 2017-11-22)
Primary citation
Chen, L.,Durr, K.L.,Gouaux, E.
X-ray structures of AMPA receptor-cone snail toxin complexes illuminate activation mechanism.
Science, 345:1021-1026, 2014
PubMed: 25103405 (PDB entries with the same primary citation)
DOI: 10.1126/science.1258409
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.258903.6%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload