4U22

GluA2flip sLBD complexed with FW and (R,R)-2b crystal form D

Summary for 4U22

Entry DOI	10.2210/pdb4u22/pdb
Descriptor	Glutamate receptor 2, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, N,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamide, ... (4 entities in total)
Functional Keywords	ampa receptor, transport protein, membrane protein
Biological source	Rattus norvegicus (Rat) More
Cellular location	Cell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains	1
Total formula weight	29891.51
Authors	Chen, L.,Gouaux, E. (deposition date: 2014-07-16, release date: 2014-08-20, Last modification date: 2023-12-27)
Primary citation	Durr, K.L.,Chen, L.,Stein, R.A.,De Zorzi, R.,Folea, I.M.,Walz, T.,Mchaourab, H.S.,Gouaux, E. Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States. Cell, 158:778-792, 2014 Cited by PubMed: 25109876 DOI: 10.1016/j.cell.2014.07.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4409 Å)

Structure validation