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4U22

GluA2flip sLBD complexed with FW and (R,R)-2b crystal form D

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AGlutamate receptor 2polymer26329193.71UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Pfam (PF00497)
In PDB
Rattus norvegicus (Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2A2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACIDnon-polymer217.21Chemie (FWD)
3AN,N'-[biphenyl-4,4'-diyldi(2R)propane-2,1-diyl]dipropane-2-sulfonamidenon-polymer480.71Chemie (FWF)
4waterwater18.0383Chemie (HOH)
Sequence modifications
A: 3 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 2-expression tag
A: 120 - 263 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Ser 263Ala 796engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29193.7
Non-Polymers*Number of molecules2
Total formula weight697.8
All*Total formula weight29891.5
*Water molecules are not included.

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PDB entries from 2024-04-24

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