ATP-bound structure of human platelet phosphofructokinase in an R-state, crystal form II

Summary for 4U1R

Related4OMT 4WL0 4RH3 4XZ2 3OPY
DescriptorATP-dependent 6-phosphofructokinase, platelet type, ADENOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION (3 entities in total)
Functional Keywordshuman platelet phosphofructokinase, r-state, allostery, atp, adp, f6p, f16bp, transferase
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm  Q01813
Total number of polymer chains4
Total molecular weight327615.75
Kloos, M.,Straeter, N. (deposition date: 2014-07-16, release date: 2015-06-03, Last modification date: 2015-08-05)
Primary citation
Kloos, M.,Bruser, A.,Kirchberger, J.,Schoneberg, T.,Strater, N.
Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation.
Biochem.J., 469:421-432, 2015
PubMed: 26205495 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20150251
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19890.4%2.4%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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