4TUZ
Crystal structure of hERa-LBD (Y537S) in complex with alpha-zearalenol
Summary for 4TUZ
Entry DOI | 10.2210/pdb4tuz/pdb |
Related | 4MG8 |
Descriptor | Estrogen receptor, Nuclear receptor coactivator 1, (3S,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, ... (7 entities in total) |
Functional Keywords | nuclear hormone receptor ligand binding domain endocrine disruptor environmental compound, nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 62473.47 |
Authors | Delfosse, V.,Grimaldi, M.,Bourguet, W. (deposition date: 2014-06-25, release date: 2015-01-28, Last modification date: 2023-12-20) |
Primary citation | Delfosse, V.,Maire, A.L.,Balaguer, P.,Bourguet, W. A structural perspective on nuclear receptors as targets of environmental compounds. Acta Pharmacol. Sin., 36:88-101, 2015 Cited by PubMed: 25500867DOI: 10.1038/aps.2014.133 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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