4TU6
Crystal structure of apo ATAD2A bromodomain with N1064 alternate conformation
Summary for 4TU6
Entry DOI | 10.2210/pdb4tu6/pdb |
Related | 4TT2 4TT4 4TT6 4TTE 4TU4 |
Descriptor | ATPase family AAA domain-containing protein 2, SULFATE ION (3 entities in total) |
Functional Keywords | bromodomain- conserved asparagine conformations, gene regulation |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q6PL18 |
Total number of polymer chains | 4 |
Total formula weight | 62198.31 |
Authors | Poncet-Montange, G.,Zhan, Y.,Bardenhagen, J.,Petrocchi, A.,Leo, E.,Shi, X.,Lee, G.,Leonard, P.,Geck Do, M.,Cardozo, M.,Palmer, W.,Andersen, J.,Jones, P.,Ladbury, J. (deposition date: 2014-06-23, release date: 2014-12-24, Last modification date: 2023-09-27) |
Primary citation | Poncet-Montange, G.,Zhan, Y.,Bardenhagen, J.P.,Petrocchi, A.,Leo, E.,Shi, X.,Lee, G.R.,Leonard, P.G.,Geck Do, M.K.,Cardozo, M.G.,Andersen, J.N.,Palmer, W.S.,Jones, P.,Ladbury, J.E. Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem.J., 466:337-346, 2015 Cited by PubMed: 25486442DOI: 10.1042/BJ20140933 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
Download full validation report