4TU3

Crystal structure of yeast Sac1/Vps74 complex

Summary for 4TU3

Entry DOI	10.2210/pdb4tu3/pdb
Descriptor	Phosphoinositide phosphatase SAC1, Vacuolar protein sorting-associated protein 74 (2 entities in total)
Functional Keywords	protein complex, phosphoric monoester hydrolases, phosphatidylinositol phosphates, golgi apparatus, hydrolase-protein transport complex, hydrolase/protein transport
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Cellular location	Endoplasmic reticulum membrane; Single-pass membrane protein: P32368 Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side: Q06385
Total number of polymer chains	2
Total formula weight	110549.09
Authors	Cai, Y.,Horenkamp, F.A.,Reinisch, K.R. (deposition date: 2014-06-23, release date: 2014-08-27, Last modification date: 2023-09-27)
Primary citation	Cai, Y.,Deng, Y.,Horenkamp, F.,Reinisch, K.M.,Burd, C.G. Sac1-Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus. J.Cell Biol., 206:485-491, 2014 Cited by PubMed: 25113029 DOI: 10.1083/jcb.201404041 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.187 Å)

Structure validation