4TT6

Crystal structure of ATAD2A bromodomain double mutant N1063A-Y1064A in apo form

Summary for 4TT6

Entry DOI	10.2210/pdb4tt6/pdb
Related	4TT2 4TT4 4TTE 4TU4 4TU6
Descriptor	ATPase family AAA domain-containing protein 2, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	acetyllysine reader deficient bromodomain, gene regulation
Biological source	Homo sapiens (Human)
Cellular location	Nucleus : Q6PL18
Total number of polymer chains	1
Total formula weight	15542.00
Authors	Poncet-Montange, G.,Zhan, Y.,Bardenhagen, J.,Petrocchi, A.,Leo, E.,Shi, X.,Lee, G.,Leonard, P.,Geck Do, M.,Cardozo, M.,Palmer, W.,Andersen, J.,Jones, P.,Ladbury, J. (deposition date: 2014-06-19, release date: 2014-12-24, Last modification date: 2023-09-27)
Primary citation	Poncet-Montange, G.,Zhan, Y.,Bardenhagen, J.P.,Petrocchi, A.,Leo, E.,Shi, X.,Lee, G.R.,Leonard, P.G.,Geck Do, M.K.,Cardozo, M.G.,Andersen, J.N.,Palmer, W.S.,Jones, P.,Ladbury, J.E. Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2. Biochem.J., 466:337-346, 2015 Cited by PubMed: 25486442 DOI: 10.1042/BJ20140933 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation