4TRM

Structure of the apo form of InhA from Mycobacterium tuberculosis

Summary for 4TRM

Entry DOI	10.2210/pdb4trm/pdb
Related	4TRN 4TRO
Descriptor	Enoyl-[acyl-carrier-protein] reductase [NADH], 2-(N-MORPHOLINO)-ETHANESULFONIC ACID (3 entities in total)
Functional Keywords	enoyl reductase, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	6
Total formula weight	171523.92
Authors	Chollet, A.,Julien, S.,Mourey, L.,Maveyraud, L. (deposition date: 2014-06-17, release date: 2015-04-29, Last modification date: 2023-12-20)
Primary citation	Chollet, A.,Mourey, L.,Lherbet, C.,Delbot, A.,Julien, S.,Baltas, M.,Bernadou, J.,Pratviel, G.,Maveyraud, L.,Bernardes-Genisson, V. Crystal structure of the enoyl-ACP reductase of Mycobacterium tuberculosis (InhA) in the apo-form and in complex with the active metabolite of isoniazid pre-formed by a biomimetic approach. J.Struct.Biol., 190:328-337, 2015 Cited by PubMed: 25891098 DOI: 10.1016/j.jsb.2015.04.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation