4TNB
Crystal Structure of G Protein-Coupled Receptor Kinase 5 in Complex with Sangivamycin
Summary for 4TNB
| Entry DOI | 10.2210/pdb4tnb/pdb |
| Related | 4TND |
| Descriptor | G protein-coupled receptor kinase 5, SANGIVAMYCIN (3 entities in total) |
| Functional Keywords | grk5-sangivamycin complex, gpcr kinase, kinase, inhibitor, signaling protein |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm: P34947 |
| Total number of polymer chains | 1 |
| Total formula weight | 68251.95 |
| Authors | Bhardwaj, A.,Komolov, K.E.,Benovic, J.L. (deposition date: 2014-06-03, release date: 2015-06-10, Last modification date: 2023-09-27) |
| Primary citation | Komolov, K.E.,Bhardwaj, A.,Benovic, J.L. Atomic Structure of G Protein-Coupled Receptor Kinase 5 (GRK5) Reveals Distinct Structural Features Novel for GRKs. J.Biol.Chem., 2015 Cited by PubMed: 26032409DOI: 10.1074/jbc.M115.647297 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.113 Å) |
Structure validation
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