4TNB
Crystal Structure of G Protein-Coupled Receptor Kinase 5 in Complex with Sangivamycin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G protein-coupled receptor kinase 5 | polymer | 590 | 67942.7 | 1 | UniProt (P34947) Pfam (PF00615) Pfam (PF00069) | Homo sapiens (Human) | G protein-coupled receptor kinase GRK5 |
| 2 | B (A) | SANGIVAMYCIN | non-polymer | 309.3 | 1 | Chemie (SGV) PubChem (16760643) PubChem (5153) PubChem (14978) PubChem (44330426) PubChem (57685061) PubChem (46875748) PubChem (70829033) PubChem (3007220) PubChem (89687375) PubChem (92209899) PubChem (92209900) PubChem (92209901) PubChem (6712998) PubChem (101037982) PubChem (10403057) PubChem (10448038) PubChem (142650208) PubChem (162968206) | |||
| 3 | C (A) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A: 1 - 590 (UniProt: P34947)
| PDB | External Database | Details |
|---|---|---|
| Lys 104 | Glu 104 | conflict |
| His 304 | Arg 304 | conflict |
| Glu 438 | Gly 438 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 67942.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 309.3 | |
| All* | Total formula weight | 68252.0 |






