4TN3

Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha

4TN3 の概要

• エントリーDOI: 10.2210/pdb4tn3/pdb
• 分子名称: TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION (2 entities in total)
• 機能のキーワード: trim protein coiled-coil scaffold retroviral restriction factor, antiviral protein
• 由来する生物種: Macaca mulatta (Rhesus macaque); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 92931.19

構造登録者

Kirkpatrick, J.J.,Stoye, J.P.,Taylor, I.A.,Goldstone, D.C. (登録日: 2014-06-03, 公開日: 2014-07-16, 最終更新日: 2023-09-27)

• 主引用文献: Goldstone, D.C.,Walker, P.A.,Calder, L.J.,Coombs, P.J.,Kirkpatrick, J.,Ball, N.J.,Hilditch, L.,Yap, M.W.,Rosenthal, P.B.,Stoye, J.P.,Taylor, I.A.; Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.; Proc.Natl.Acad.Sci.USA, 111:9609-9614, 2014; PubMed: 24979782; DOI: 10.1073/pnas.1402448111

実験手法

X-RAY DIFFRACTION (3.1989 Å)