4S0Z
Crystal structure of M26V human DJ-1
Summary for 4S0Z
Entry DOI | 10.2210/pdb4s0z/pdb |
Related | 1P5F 2RK4 3B36 |
Descriptor | Protein DJ-1, 1,2-ETHANEDIOL, ACETATE ION, ... (4 entities in total) |
Functional Keywords | dj-1/thij/pfpi superfamily, oxidative stress response, chaperone |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane ; Lipid-anchor : Q99497 |
Total number of polymer chains | 1 |
Total formula weight | 20474.58 |
Authors | Milkovic, N.M.,Wilson, M.A. (deposition date: 2015-01-07, release date: 2015-08-05, Last modification date: 2023-09-20) |
Primary citation | Milkovic, N.M.,Catazaro, J.,Lin, J.,Halouska, S.,Kizziah, J.L.,Basiaga, S.,Cerny, R.L.,Powers, R.,Wilson, M.A. Transient sampling of aggregation-prone conformations causes pathogenic instability of a parkinsonian mutant of DJ-1 at physiological temperature. Protein Sci., 24:1671-1685, 2015 Cited by PubMed: 26234586DOI: 10.1002/pro.2762 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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