4S0N

Crystal Structure of HLTF HIRAN Domain bound to DNA

Summary for 4S0N

• Entry DOI: 10.2210/pdb4s0n/pdb
• Descriptor: Helicase-like transcription factor, 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', THYMIDINE-5'-MONOPHOSPHATE, ... (6 entities in total)
• Functional Keywords: alpha+beta, dna 3'-end binding, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q14527
• Total number of polymer chains: 8
• Total formula weight: 69641.26

Authors

Chavez, D.A.,Eichman, B.F. (deposition date: 2015-01-02, release date: 2015-05-27, Last modification date: 2024-02-28)

• Primary citation: Kile, A.C.,Chavez, D.A.,Bacal, J.,Eldirany, S.,Korzhnev, D.M.,Bezsonova, I.,Eichman, B.F.,Cimprich, K.A.; HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.; Mol.Cell, 58:1090-1100, 2015; PubMed: 26051180; DOI: 10.1016/j.molcel.2015.05.013

Experimental method

X-RAY DIFFRACTION (1.501 Å)