4S0N
Crystal Structure of HLTF HIRAN Domain bound to DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Helicase-like transcription factor | polymer | 130 | 14183.2 | 4 | UniProt (Q14527) Pfam (PF08797) In PDB | Homo sapiens (human) | DNA-binding protein/plasminogen activator inhibitor 1 regulator, HIP116, RING finger protein 80, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3, Sucrose nonfermenting protein 2-like 3 |
| 2 | E, F, G, H | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3' | polymer | 10 | 2997.0 | 4 | synthetic construct | ||
| 3 | A | THYMIDINE-5'-MONOPHOSPHATE | non-polymer | 322.2 | 2 | Chemie (DT) | |||
| 4 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | A, B, C, D | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | water | water | 18.0 | 589 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 55 - 180 (UniProt: Q14527)
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | expression tag |
| Pro 52 | - | expression tag |
| Gly 53 | - | expression tag |
| Ser 54 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 68720.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 920.6 | |
| All* | Total formula weight | 69641.3 |
