4RWV
Crystal structure of PIP3 bound human nuclear receptor LRH-1 (Liver Receptor Homolog 1, NR5A2) in complex with a co-regulator DAX-1 (NR0B1) peptide at 1.86 A resolution
4RWV の概要
エントリーDOI | 10.2210/pdb4rwv/pdb |
分子名称 | Nuclear receptor subfamily 5 group A member 2, Nuclear receptor DAX1, (2S)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dihexadecanoate, ... (6 entities in total) |
機能のキーワード | ligand-binding domain of nuclear hormone receptor, pf00104 family, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-biology, partnership for stem cell biology, transcription, stemcell |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Nucleus : O00482 F1D8P4 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 31868.46 |
構造登録者 | Joint Center for Structural Genomics (JCSG),Partnership for Stem Cell Biology,Partnership for Stem Cell Biology (STEMCELL) (登録日: 2014-12-05, 公開日: 2015-01-21, 最終更新日: 2023-12-06) |
主引用文献 | Joint Center for Structural Genomics (JCSG),Partnership for Stem Cell Biology Crystal structure of a Homo sapiens hepatocytic transcription factor hB1F-2 (B1F2) in complex with nuclear receptor subfamily 0 group B member 1 (NR0B1, residues 140-154) from human at 1.86 A resolution To be published, |
実験手法 | X-RAY DIFFRACTION (1.859 Å) |
構造検証レポート
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