4RUO

Crystal structure of zVDR L337H mutant-gemini complex

4RUO の概要

• エントリーDOI: 10.2210/pdb4ruo/pdb
• 関連するPDBエントリー: 2HC4 2HCD 4RUJ 4RUP
• 分子名称: Vitamin D3 receptor A, Nuclear receptor coactivator 2, 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ... (4 entities in total)
• 機能のキーワード: alpha helical sandwich, transcription factor, retinoid x receptor, ligand, dna, phosphorylation, nucleus, transcription factor-transcription regulator complex, transcription factor/transcription regulator
• 由来する生物種: Danio rerio (leopard danio,zebra danio,zebra fish); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36168.30

構造登録者

Huet, T.,Moras, D.,Rochel, N. (登録日: 2014-11-21, 公開日: 2015-10-07, 最終更新日: 2024-02-28)

• 主引用文献: Huet, T.,Laverny, G.,Ciesielski, F.,Molnar, F.,Ramamoorthy, T.G.,Belorusova, A.Y.,Antony, P.,Potier, N.,Metzger, D.,Moras, D.,Rochel, N.; A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects.; Cell Rep, 10:516-526, 2015; PubMed: 25620699; DOI: 10.1016/j.celrep.2014.12.045

実験手法

X-RAY DIFFRACTION (2.805 Å)