4RSU

Crystal structure of the light and hvem complex

Summary for 4RSU

• Entry DOI: 10.2210/pdb4rsu/pdb
• Related: 2AW2 4FHQ 4J6G
• Descriptor: Tumor necrosis factor ligand superfamily member 14, soluble form, Tumor necrosis factor receptor superfamily member 14, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: structural genomics, psi-biology, new york structural genomics, research consortium, nysgrc, immunity, n-glycosylation, membrane, secreted protein, cytokine, ifn, jelly-roll fold, protein structure initiative, atoms-to-animals: the immune function network, cysteine rich domain, signaling, cell membrane, secreted, immune system, new york structural genomics research consortium
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 197463.48

Authors

Liu, W.,Ramagoal, U.A.,Himmel, D.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.,Atoms-to-Animals: The Immune Function Network (IFN),New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2014-11-11, release date: 2015-02-04, Last modification date: 2023-09-20)

• Primary citation: Liu, W.,Chou, T.F.,Garrett-Thomson, S.C.,Seo, G.Y.,Fedorov, E.,Ramagopal, U.A.,Bonanno, J.B.,Wang, Q.,Kim, K.,Garforth, S.J.,Kakugawa, K.,Cheroutre, H.,Kronenberg, M.,Almo, S.C.; HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.; J.Exp.Med., 218:-, 2021; PubMed: 34709351; DOI: 10.1084/jem.20211112

Experimental method

X-RAY DIFFRACTION (2.3 Å)