4RSU

Crystal structure of the light and hvem complex

4RSU の概要

• エントリーDOI: 10.2210/pdb4rsu/pdb
• 関連するPDBエントリー: 2AW2 4FHQ 4J6G
• 分子名称: Tumor necrosis factor ligand superfamily member 14, soluble form, Tumor necrosis factor receptor superfamily member 14, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: structural genomics, psi-biology, new york structural genomics, research consortium, nysgrc, immunity, n-glycosylation, membrane, secreted protein, cytokine, ifn, jelly-roll fold, protein structure initiative, atoms-to-animals: the immune function network, cysteine rich domain, signaling, cell membrane, secreted, immune system, new york structural genomics research consortium
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 197463.48

構造登録者

Liu, W.,Ramagoal, U.A.,Himmel, D.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.,Atoms-to-Animals: The Immune Function Network (IFN),New York Structural Genomics Research Consortium (NYSGRC) (登録日: 2014-11-11, 公開日: 2015-02-04, 最終更新日: 2023-09-20)

• 主引用文献: Liu, W.,Chou, T.F.,Garrett-Thomson, S.C.,Seo, G.Y.,Fedorov, E.,Ramagopal, U.A.,Bonanno, J.B.,Wang, Q.,Kim, K.,Garforth, S.J.,Kakugawa, K.,Cheroutre, H.,Kronenberg, M.,Almo, S.C.; HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160.; J.Exp.Med., 218:-, 2021; PubMed: 34709351; DOI: 10.1084/jem.20211112

実験手法

X-RAY DIFFRACTION (2.3 Å)