4RKZ

Crystal Structure of Mevalonate-3-Kinase from Thermoplasma acidophilum (Mevalonate 3-Phosphate/ADP Bound)

4RKZ の概要

• エントリーDOI: 10.2210/pdb4rkz/pdb
• 関連するPDBエントリー: 4RKP 4RKS
• 分子名称: Putative uncharacterized protein Ta1305, ADENOSINE-5'-DIPHOSPHATE, (3R)-5-hydroxy-3-methyl-3-(phosphonooxy)pentanoic acid, ... (5 entities in total)
• 機能のキーワード: mevalonate, mevalonate-3-kinase, mevalonate pyrophosphate decarboxylase, mevalonate diphosphate decarboxylase, mevalonic acid, mevalonate kinase, transferase
• 由来する生物種: Thermoplasma acidophilum
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75824.64

構造登録者

Vinokur, J.M.,Cascio, D.,Sawaya, M.R.,Bowie, J.U. (登録日: 2014-10-14, 公開日: 2014-12-10, 最終更新日: 2023-09-20)

• 主引用文献: Vinokur, J.M.,Korman, T.P.,Sawaya, M.R.,Collazo, M.,Cascio, D.,Bowie, J.U.; Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases.; Protein Sci., 24:212-220, 2015; PubMed: 25422158; DOI: 10.1002/pro.2607

実験手法

X-RAY DIFFRACTION (2.3 Å)