4RHG

Crystal structure of PTPN3 (PTPH1) D811E, C842S mutant in complex with Eps15 pTyr849 peptide

Summary for 4RHG

• Entry DOI: 10.2210/pdb4rhg/pdb
• Related: 2B49 4RH5 4RH9 4RI4 4RI5
• Descriptor: Tyrosine-protein phosphatase non-receptor type 3, Epidermal growth factor receptor substrate 15 (3 entities in total)
• Functional Keywords: alpha beta, hydrolase, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 36069.70

Authors

Chen, K.-E.,Meng, T.C.,Wang, A.H.-J. (deposition date: 2014-10-02, release date: 2015-03-11, Last modification date: 2023-12-06)

• Primary citation: Chen, K.E.,Li, M.Y.,Chou, C.C.,Ho, M.R.,Chen, G.C.,Meng, T.C.,Wang, A.H.; Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.; Structure, 23:653-664, 2015; PubMed: 25728925; DOI: 10.1016/j.str.2015.01.017

Experimental method

X-RAY DIFFRACTION (1.581 Å)