4RF5

Crystal structure of ketoreductase from Lactobacillus kefir, E145S mutant

Summary for 4RF5

Entry DOI	10.2210/pdb4rf5/pdb
Related	4RF2 4RF3 4RF4
Descriptor	NADPH dependent R-specific alcohol dehydrogenase, MAGNESIUM ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	oxidoreductase
Biological source	Lactobacillus kefiri
Total number of polymer chains	2
Total formula weight	58110.05
Authors	Tang, Y.,Tibrewal, N.,Cascio, D. (deposition date: 2014-09-24, release date: 2015-09-30, Last modification date: 2023-09-20)
Primary citation	Noey, E.L.,Tibrewal, N.,Jimenez-Oses, G.,Osuna, S.,Park, J.,Bond, C.M.,Cascio, D.,Liang, J.,Zhang, X.,Huisman, G.W.,Tang, Y.,Houk, K.N. Origins of stereoselectivity in evolved ketoreductases. Proc.Natl.Acad.Sci.USA, 112:E7065-E7072, 2015 Cited by PubMed: 26644568 DOI: 10.1073/pnas.1507910112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.596 Å)

Structure validation