4RF2

Crystal structure of NADP+ bound ketoreductase from Lactobacillus kefir

Summary for 4RF2

Entry DOI	10.2210/pdb4rf2/pdb
Related	4RF3 4RF4 4RF5
Descriptor	NADPH dependent R-specific alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	oxidoreductase
Biological source	Lactobacillus kefiri
Total number of polymer chains	2
Total formula weight	59521.04
Authors	Tang, Y.,Tibrewal, N.,Cascio, D. (deposition date: 2014-09-24, release date: 2015-09-30, Last modification date: 2023-09-20)
Primary citation	Noey, E.L.,Tibrewal, N.,Jimenez-Oses, G.,Osuna, S.,Park, J.,Bond, C.M.,Cascio, D.,Liang, J.,Zhang, X.,Huisman, G.W.,Tang, Y.,Houk, K.N. Origins of stereoselectivity in evolved ketoreductases. Proc.Natl.Acad.Sci.USA, 112:E7065-E7072, 2015 Cited by PubMed: 26644568 DOI: 10.1073/pnas.1507910112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.089 Å)

Structure validation