4RF2

Crystal structure of NADP+ bound ketoreductase from Lactobacillus kefir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	NADPH dependent R-specific alcohol dehydrogenase	polymer	272	28980.7	2	UniProt (Q6WVP7) Pfam (PF13561)	Lactobacillus kefiri	Ketoreductase
2	C, F (A, B)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	D, E, G (A, B)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
4	H, I (A, B)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A, B: 1 - 252 (UniProt: Q6WVP7)

PDB	External Database	Details
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Gly -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	57961.3
Non-Polymers*	Number of molecules	5
	Total formula weight	1559.7
All*	Total formula weight	59521.0

*Water molecules are not included.