4RE6
Acylaminoacyl peptidase complexed with a chloromethylketone inhibitor
Summary for 4RE6
Entry DOI | 10.2210/pdb4re6/pdb |
Related | 4RE5 |
Related PRD ID | PRD_001053 |
Descriptor | Acylamino-acid-releasing enzyme, N-[(benzyloxy)carbonyl]glycyl-N-[(2S,3R)-4-chloro-3-hydroxy-1-phenylbutan-2-yl]glycinamide, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | beta-propeller, alpha-beta-hydrolase fold, chloromethyl-ketone inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Aeropyrum pernix |
Total number of polymer chains | 4 |
Total formula weight | 253542.75 |
Authors | Menyhard, D.K.,Orgovan, Z.,Szeltner, Z.,Szamosi, I.,Harmat, V. (deposition date: 2014-09-22, release date: 2015-01-28, Last modification date: 2023-09-20) |
Primary citation | Menyhard, D.K.,Orgovan, Z.,Szeltner, Z.,Szamosi, I.,Harmat, V. Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality. Acta Crystallogr.,Sect.D, 71:461-472, 2015 Cited by PubMed: 25760596DOI: 10.1107/S1399004714026819 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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