4RC4

Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives

Summary for 4RC4

• Entry DOI: 10.2210/pdb4rc4/pdb
• Related: 4I41 4RBL 4RC2 4RC3
• Descriptor: Serine/threonine-protein kinase pim-1, 1,4-bis[(2-aminoethyl)amino]-5,8-dihydroxyanthracene-9,10-dione (2 entities in total)
• Functional Keywords: kinase, phosphorylation, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• Total number of polymer chains: 1
• Total formula weight: 33649.09

Authors

Zhang, W.,Wan, X.,Huang, N. (deposition date: 2014-09-14, release date: 2015-03-18, Last modification date: 2023-09-20)

• Primary citation: Zhang, W.,Wan, X.,Huang, N.; Crystal structure of Ser/Thr kinase Pim1 in complex with Mitoxantrone derivatives; To be Published,

Experimental method

X-RAY DIFFRACTION (2.651 Å)