4RBO
Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution
4RBO の概要
エントリーDOI | 10.2210/pdb4rbo/pdb |
分子名称 | Putative homeobox protein NANOGP8, 5'-D(*GP*GP*CP*CP*CP*AP*TP*TP*CP*AP*AP*G)-3', 5'-D(*CP*TP*TP*GP*AP*AP*TP*GP*GP*GP*CP*C)-3' (3 entities in total) |
機能のキーワード | homeobox, pf00046 family, structural genomics, joint center for structural genomics, jcsg, partnership for stem cell biology, stemcell, protein structure initiative, psi-biology, dna binding protein, transcription, transcription-dna complex, transcription/dna |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Nucleus : Q6NSW7 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 31873.46 |
構造登録者 | Joint Center for Structural Genomics (JCSG),Partnership for Stem Cell Biology (STEMCELL) (登録日: 2014-09-12, 公開日: 2014-10-01, 最終更新日: 2023-02-01) |
主引用文献 | Hayashi, Y.,Caboni, L.,Das, D.,Yumoto, F.,Clayton, T.,Deller, M.C.,Nguyen, P.,Farr, C.L.,Chiu, H.J.,Miller, M.D.,Elsliger, M.A.,Deacon, A.M.,Godzik, A.,Lesley, S.A.,Tomoda, K.,Conklin, B.R.,Wilson, I.A.,Yamanaka, S.,Fletterick, R.J. Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proc.Natl.Acad.Sci.USA, 112:4666-4671, 2015 Cited by PubMed: 25825768DOI: 10.1073/pnas.1502855112 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.3 Å) |
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