4R9Y
Crystal structure of KKOFab in complex with platelet factor 4
Summary for 4R9Y
Entry DOI | 10.2210/pdb4r9y/pdb |
Related | 4R97 4R9W |
Descriptor | Platelet factor 4, Platelet factor 4 antibody KKO light chain, Platelet factor 4 antibody KKO heavy chain (3 entities in total) |
Functional Keywords | kko, pf4, hit, immunoglobulin, cxc chemokine, antibody, antigen, blood, immune system-cytokine complex, immune system/cytokine |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted : P02776 |
Total number of polymer chains | 8 |
Total formula weight | 125212.63 |
Authors | Cai, Z.,Zhu, Z.,Liu, Q.,Greene, M.I. (deposition date: 2014-09-08, release date: 2015-12-16, Last modification date: 2017-11-22) |
Primary citation | Cai, Z.,Yarovoi, S.V.,Zhu, Z.,Rauova, L.,Hayes, V.,Lebedeva, T.,Liu, Q.,Poncz, M.,Arepally, G.,Cines, D.B.,Greene, M.I. Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6:8277-8277, 2015 Cited by PubMed: 26391892DOI: 10.1038/ncomms9277 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.11 Å) |
Structure validation
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